Description

2-Bromo-3,4,5,6-Tetrafluorobenzonitrile is a versatile fluorinated aromatic building block, distinguished by its unique combination of bromine and nitrile functional groups on a perfluorinated benzene ring. This structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where electronic properties and stability are paramount. It is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for fluorine-containing molecules where the bromine atom allows for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the stability and bioactivity imparted by the fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and other functional components in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing chemical resistance, thermal stability, and dielectric properties.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution due to the activated bromine substituent.
• Fluorinated Dye & Pigment Production: Acts as a starting material for creating dyes and pigments with superior lightfastness and chemical inertness.

Basic Information

Product Name	2-Bromo-3,4,5,6-Tetrafluorobenzonitrile
CAS No.	16583-02-1
Molecular Formula	C7BrF4N
Molecular Weight	257.98 g/mol
Synonyms	2-Bromo-3,4,5,6-tetrafluorobenzonitrile; 3,4,5,6-Tetrafluoro-2-bromobenzonitrile; Benzonitrile, 2-bromo-3,4,5,6-tetrafluoro-; 2-Bromotetrafluorobenzonitrile; 2-Bromo-3,4,5,6-tetrafluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4,5,6-Tetrafluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.