Description

11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 17-Acetate is a high-purity steroid intermediate of significant importance in the synthesis of active pharmaceutical ingredients (APIs). This compound matters because it serves as a critical building block for the production of potent corticosteroids and other therapeutic agents, where precise chemical structure and purity are paramount for efficacy and safety. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in advanced steroid chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of corticosteroid drugs such as hydrocortisone and its derivatives.
• Research & Development: Used in academic and industrial laboratories for exploring new steroid-based therapeutics and studying metabolic pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 17-Acetate
CAS No.	16463-74-4
Molecular Formula	C23H32O6
Molecular Weight	404.50 g/mol
Synonyms	Cortisol 17-acetate; Hydrocortisone 17-acetate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate; 17α-Acetoxycortisol; Reichstein's Substance S 17-acetate; 11β-Hydroxycortexolone 17-acetate; 17α-Acetoxy-11β,21-dihydroxypregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for pharmaceutical development, supported by comprehensive analytical data. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by HPLC, IR, and other pharmacopeial methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.