Description

n-[(20S)-3α-Dimethylamino-5α-Pregnan-20-yl]-n-Methylacetamide is a high-purity, steroidal alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting neurological and endocrine pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of neuroactive steroids and hormone modulators. Our supply ensures the consistent quality and reliability required for sensitive R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of neurosteroids and related therapeutic compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of steroidal APIs.
• Biochemical Research: Tool compound for investigating the structure-activity relationships (SAR) of steroids at various biological receptors.
• Preclinical Studies: Employed in the development of potential agents for neurological disorders, stress-related conditions, and hormonal imbalances.
• Process Chemistry: Serves as a starting material or intermediate in custom synthesis and process optimization for pharmaceutical manufacturing.

Basic Information

Product Name	n-[(20S)-3α-Dimethylamino-5α-Pregnan-20-yl]-n-Methylacetamide
CAS No.	15437-92-0
Molecular Formula	C₂₆H₄₆N₂O
Molecular Weight	402.66 g/mol
Synonyms	3α-(Dimethylamino)-5α-pregnan-20β-yl methylacetamide; (20S)-20-(Acetyl-methyl-amino)-3α-dimethylamino-5α-pregnane; 3α-Dimethylamino-5α-pregnan-20β-yl methylacetamide; 5α-Pregnan-3α,20β-diol, 20-(acetyl-methyl-amino)-3-(dimethylamino)-, (3α,5α,20S)-; Pregnane derivative 15437-92-0; Neurosteroid intermediate 15437-92-0
EINECS	Contact for details

Quality Control

Every batch of n-[(20S)-3α-Dimethylamino-5α-Pregnan-20-yl]-n-Methylacetamide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.