Description

1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 17-Valerate-21-Acetate CAS NO 15180-00-4 is a synthetic corticosteroid derivative, a key intermediate in the production of potent anti-inflammatory and immunosuppressive pharmaceutical agents. Its value lies in its specific chemical structure, which serves as a crucial building block for advanced steroid synthesis. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development and production of specialized corticosteroid medications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced topical and systemic corticosteroids.
• Anti-inflammatory Drug Research: Used in R&D for developing new steroid-based therapies targeting inflammation and autoimmune conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of steroid manufacturing processes within GMP environments.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Item	Details
Product Name	1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 17-Valerate-21-Acetate
CAS No.	15180-00-4
Molecular Formula	C₂₈H₃₈O₇
Molecular Weight	486.60 g/mol
Synonyms	Prednisolone 17-Valerate 21-Acetate; 11β,17,21-Trihydroxy-1,4-pregnadiene-3,20-dione 17-Valerate 21-Acetate; 17-Valeryl-21-acetylprednisolone; Prednisolone Valerate Acetate; NSC 106977; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 17α-valerate 21-acetate; 11β-Hydroxyprednisolone 17-valerate 21-acetate
EINECS	Contact for details

Quality Control

Our 1,4-Pregnadien-11-Beta, 17,21-Triol-3,20-Dione 17-Valerate-21-Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification, to ensure it meets exacting standards suitable for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.