Description

Bupranolol is a potent, non-selective β-adrenergic receptor antagonist (β-blocker) with intrinsic sympathomimetic activity. This compound is a critical active pharmaceutical ingredient (API) used in the research and development of cardiovascular therapeutics. It is essential for pharmaceutical manufacturers, research institutions, and chemical suppliers focused on cardiology and pharmacology. Bupranolol CAS NO 14556-46-8 is supplied as a high-purity material to meet stringent industry requirements.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of β-blocker medications for managing hypertension (high blood pressure), angina pectoris, and cardiac arrhythmias.
• Biochemical Research: A vital tool for studying β-adrenergic receptor mechanisms, signal transduction pathways, and the physiological effects of β-blockade.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Preclinical Studies: Used in animal models to investigate the pharmacokinetics, efficacy, and safety profiles of β-blocking agents.
• Metabolite Synthesis: Acts as a starting material or intermediate for the synthesis of related metabolites and derivatives for further pharmacological evaluation.

Basic Information

Item	Details
Product Name	Bupranolol
CAS No.	14556-46-8
Molecular Formula	C14H22ClNO2
Molecular Weight	271.79 g/mol
Synonyms	1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol; (±)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol; KL 255; Betadran; Betadrenol; Looser; Ophtorenin; Betabloccante
EINECS	Contact for details

Quality Control

Our Bupranolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.