Description

Chlorcyclizine Hydrochloride is a pharmaceutical-grade antihistamine compound, recognized for its potent H1-receptor antagonistic properties. This active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing anti-allergy and anti-emetic medications.

Application

• Pharmaceutical API: Core active ingredient in prescription and over-the-counter (OTC) antihistamine formulations for treating allergic conditions such as hay fever, urticaria, and allergic rhinitis.
• Anti-Emetic Preparations: Used in medications designed to prevent or treat nausea and vomiting, including motion sickness.
• Veterinary Pharmaceuticals: Incorporated into veterinary medicinal products for managing allergic reactions and motion sickness in animals.
• Pharmacological Research: Serves as a reference standard and key intermediate in preclinical and clinical studies investigating histamine pathways and receptor mechanisms.
• Generic Drug Manufacturing: Essential for the production of generic versions of established antihistamine drugs, ensuring cost-effective therapeutic options.

Basic Information

Product Name	Chlorcyclizine Hydrochloride
CAS No.	14362-31-3
Molecular Formula	C18H22ClN2•HCl
Molecular Weight	337.30 g/mol
Synonyms	1-(4-Chlorobenzhydryl)-4-methylpiperazine Hydrochloride; Chlorcyclizine HCl; Histachlorazine; Perazil; Diparalene; Chlorcyclizine Dihydrochloride; 1-(p-Chloro-α-phenylbenzyl)-4-methylpiperazine Hydrochloride
EINECS	238-327-6

Quality Control

Our Chlorcyclizine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles, is provided with every shipment to guarantee supply chain transparency and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.