Description

Chloroprednisone 21-Acetate is a synthetic corticosteroid derivative, specifically a halogenated and esterified form of prednisone. This compound is a crucial pharmaceutical intermediate in the synthesis of more potent and specialized anti-inflammatory and immunosuppressive steroid drugs. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in advanced steroid chemistry and novel drug development.

Application

• Key Intermediate in Steroid API Synthesis: Serves as a critical building block for the production of advanced corticosteroid active pharmaceutical ingredients (APIs).
• Pharmaceutical Research & Development: Used in medicinal chemistry programs to develop new steroid-based therapeutics with modified potency and metabolic profiles.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid products.
• Biochemical Research: Utilized in studies investigating glucocorticoid receptor binding, metabolism, and structure-activity relationships (SAR).

Basic Information

Product Name	Chloroprednisone 21-Acetate
CAS No.	14066-79-6
Molecular Formula	C23H28ClO6
Molecular Weight	435.92 g/mol
Synonyms	21-Acetoxy-6-chloro-17α-hydroxypregna-1,4-diene-3,11,20-trione; 6-Chloro-17α,21-dihydroxypregna-1,4-diene-3,11,20-trione 21-acetate; 6-Chloroprednisone 21-acetate; Chloroprednison-21-acetat; 6-Chloro-δ1-cortisone 21-acetate
EINECS	Contact for details

Quality Control

Our Chloroprednisone 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.