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(13α,17α)-1α,3α-Diacetoxy-14β,15β:21,23-Diepoxy-7α-Hydroxy-4,4,8-Trimethyl-24-Nor-5α-Chola-20,22-Dien-16-One CAS NO 14051-20-8


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CAS No.:14051-20-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(13α,17α)-1α,3α-Diacetoxy-14β,15β:21,23-Diepoxy-7α-Hydroxy-4,4,8-Trimethyl-24-Nor-5α-Chola-20,22-Dien-16-One CAS NO 14051-20-8 is a high-purity, complex steroidal intermediate with a unique epoxide and diacetoxy functional group architecture. This compound is of significant value in advanced pharmaceutical synthesis, particularly as a key precursor for the development of novel therapeutic agents. It is primarily required by research institutions and fine chemical manufacturers specializing in steroid chemistry, hormone analogs, and targeted drug discovery.

Application

  • Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
  • Research & Development: Used in academic and industrial R&D for exploring new chemical entities (NCEs) with potential biological activity.
  • Steroid Derivative Synthesis: Serves as a precursor for creating modified steroids with tailored properties for medicinal chemistry.
  • Biochemical Research: Employed in studies investigating steroid receptor interactions and metabolic pathways.
  • Fine Chemical Production: Utilized in the manufacture of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Item Details
Product Name (13α,17α)-1α,3α-Diacetoxy-14β,15β:21,23-Diepoxy-7α-Hydroxy-4,4,8-Trimethyl-24-Nor-5α-Chola-20,22-Dien-16-One
CAS No. 14051-20-8
Molecular Formula C₂₉H₃₈O₈
Molecular Weight 514.61 g/mol
Synonyms 1α,3α-Diacetoxy-14β,15β:21,23-diepoxy-7α-hydroxy-4,4,8-trimethyl-24-nor-5α-chola-20,22-dien-16-one; 24-Nor-5α-chola-20,22-diene-1α,3α,7α-triol, 1,3-diacetate 14,15:21,23-diepoxide; 14051-20-8; Steroidal diepoxide intermediate; 1,3-Diacetoxy-14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-24-nor-5α-chol-20-en-16-one
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Quality Control

Our (13α,17α)-1α,3α-Diacetoxy-14β,15β:21,23-Diepoxy-7α-Hydroxy-4,4,8-Trimethyl-24-Nor-5α-Chola-20,22-Dien-16-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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