Description

Tetrahydroaldosterone is a key metabolite and reference standard in the study of the renin-angiotensin-aldosterone system (RAAS). This compound is essential for researchers and manufacturers requiring precise analytical benchmarks for hormone metabolism and related endocrine pathways. It is primarily utilized in pharmaceutical R&D, clinical diagnostics, and the production of high-purity biochemical reagents for metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative analysis of aldosterone and its metabolites in drug development and bioanalytical studies.
• Clinical Research & Diagnostics: Serves as a critical calibrator in LC-MS/MS and immunoassay methods for accurately measuring hormone levels in patient samples for conditions like hypertension and adrenal disorders.
• Biochemical Research: Employed in metabolic pathway studies to investigate the enzymatic conversion and biological activity of steroid hormones.
• API Intermediate: Acts as a high-purity synthetic intermediate in the production of specialized steroid-based active pharmaceutical ingredients (APIs).
• Quality Control Laboratories: Provides an essential benchmark for internal quality control and method validation in pharmaceutical and contract testing laboratories.

Basic Information

Product Name	Tetrahydroaldosterone
CAS No.	13489-75-3
Molecular Formula	C21H34O5
Molecular Weight	366.49 g/mol
Synonyms	3α,5β-Tetrahydroaldosterone; 3α,11β,21-Trihydroxy-20-oxo-5β-pregnan-18-al; 18,11-Hemiacetal of 3α,5β-tetrahydroaldosterone; Aldosterone metabolite; TH-ALD; 5β-Tetrahydroaldosterone; 3α,5β-TH-ALD; 11β,21-Dihydroxy-3,20-dioxo-5β-pregnan-18-al
EINECS	Contact for details

Quality Control

Our Tetrahydroaldosterone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and reference standard use. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.