Description

17-Dehydroxy Prednisolone is a key pharmaceutical intermediate and a derivative of the corticosteroid prednisolone. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and for research into anti-inflammatory mechanisms. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in steroid chemistry and drug development.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced corticosteroid APIs and other steroid derivatives.
• Research & Development: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for novel therapeutic steroid compounds.

Basic Information

Product Name	17-Dehydroxy Prednisolone
CAS No.	13479-38-4
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione; 17-Desoxyprednisolone; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione; Prednisolone, 17-dehydroxy-
EINECS	Contact for details

Quality Control

Our 17-Dehydroxy Prednisolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.