Description

16α-Methyl Prednisolone 21-Acetate is a synthetic glucocorticoid steroid derivative, widely recognized for its potent anti-inflammatory and immunosuppressive properties. This high-purity intermediate is critical for ensuring the efficacy and safety of finished pharmaceutical products. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of advanced corticosteroid medications.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Production: Used in the manufacture of medications for treating conditions like rheumatoid arthritis, severe allergies, and asthma.
• Immunosuppressive Therapy: A critical component in drugs designed to prevent organ transplant rejection and manage autoimmune diseases.
• Dermatological Preparations: Incorporated into topical creams and ointments for treating severe skin inflammations and conditions like eczema or psoriasis.
• Veterinary Medicine: Employed in formulations for treating inflammatory and allergic conditions in animals.
• Research & Development: Serves as a reference standard and building block in pharmacological and biochemical research exploring steroid action.

Basic Information

Product Name	16α-Methyl Prednisolone 21-Acetate
CAS No.	13209-52-4
Molecular Formula	C₂₄H₃₂O₆
Molecular Weight	416.51 g/mol
Synonyms	16α-Methylprednisolone 21-acetate; Medrol Acetate; 16α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate; 16α-Methylprednisolone acetate; 16α-Methyl-δ¹-prednisolone 21-acetate; 11β,17α,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate; 16α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our 16α-Methyl Prednisolone 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.