Description

21-o-Acetyl 6β-Hydroxy Cortisol is a key synthetic steroid derivative and an important intermediate in the production of more complex corticosteroid compounds. This compound matters for its role in pharmaceutical research and development, particularly in the synthesis of novel anti-inflammatory and immunosuppressive agents. It is needed by pharmaceutical manufacturers, research institutions, and fine chemical synthesis companies engaged in advanced steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced corticosteroid APIs (Active Pharmaceutical Ingredients).
• Biochemical Research: Used as a reference standard or probe in metabolic studies of cortisol and related steroid hormones.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of other acetylated or hydroxylated steroid analogs.
• Drug Discovery & Development: Employed in medicinal chemistry programs to explore structure-activity relationships (SAR) of steroid-based therapeutics.

Basic Information

Product Name	21-o-Acetyl 6β-Hydroxy Cortisol
CAS No.	13096-53-2
Molecular Formula	C₂₃H₃₂O₇
Molecular Weight	420.50 g/mol
Synonyms	6β-Hydroxycortisol 21-acetate; 21-Acetyl-6β-hydroxycortisol; 11β,17α,21-Trihydroxy-6β-pregn-4-ene-3,20-dione 21-acetate; Cortisol 21-acetate, 6β-hydroxy-; 6β-Hydroxyhydrocortisone 21-acetate; 21-O-Acetyl-6β-hydroxycortisol; 6β-Hydroxycortisol acetate
EINECS	Contact for details

Quality Control

Our 21-o-Acetyl 6β-Hydroxy Cortisol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.