Description

Mazipredone is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical formulations, valued for its specific glucocorticoid receptor activity. It is primarily utilized by research institutions and pharmaceutical manufacturers developing treatments for inflammatory and autoimmune conditions, as well as in the production of specialized veterinary medicines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new treatments for arthritis, dermatitis, and other inflammatory diseases.
• Immunosuppressive Therapy Development: Serves as a reference compound in studies targeting autoimmune disorders like lupus and rheumatoid arthritis.
• Veterinary Medicine: Employed in formulating anti-inflammatory and anti-allergic treatments for companion and livestock animals.
• Biochemical Research: Used as a tool compound to study glucocorticoid receptor pathways and mechanisms of action.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.

Basic Information

Product Name	Mazipredone
CAS No.	13085-08-0
Molecular Formula	C₂₄H₃₂O₆
Molecular Weight	416.51 g/mol
Synonyms	Mazipredone; Depersolon; 11β,17α,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione; 6α-Methylprednisolone; 6α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; U-8471; SH-742
EINECS	Contact for details

Quality Control

Our Mazipredone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.