Description

Sibiromycin is a potent anthracycline antibiotic compound with significant research interest due to its unique biological activity. Its primary value lies in its role as a critical reference standard and active pharmaceutical ingredient (API) in advanced pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors focusing on oncology and antimicrobial discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of sibiromycin in research and quality control laboratories.
• Oncology Research: Serves as a key investigational compound in studies targeting DNA intercalation and topoisomerase inhibition for cancer therapy development.
• Antimicrobial Agent Development: Investigated for its potent activity against a spectrum of bacteria, supporting the discovery of new antibiotic classes.
• Biochemical Research: Utilized in mechanistic studies to understand the interaction of anthracycline drugs with biological macromolecules.
• API Intermediate: Acts as a high-purity building block in the synthesis of novel derivatives or more complex therapeutic agents.

Basic Information

Product Name	Sibiromycin
CAS No.	12684-33-2
Molecular Formula	C₃₂H₃₅NO₁₂
Molecular Weight	625.62 g/mol
Synonyms	Antibiotic BU 2231; BU-2231; NSC-267213; 7-O-Methylnogalarol; 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our Sibiromycin is produced and handled under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.