Description

Bleomycin A2 is a potent glycopeptide antibiotic and a primary component of the bleomycin complex, widely recognized for its antitumor activity. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of chemotherapeutic agents. It is essential for pharmaceutical manufacturers and research institutions focused on oncology drug development and biochemical research. The product is supplied as a high-purity material to ensure efficacy and safety in its intended applications.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of injectable chemotherapeutic drugs.
• Biochemical research tool for studying DNA cleavage mechanisms and cell cycle arrest.
• Reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Key component in preclinical and clinical studies for novel cancer treatment formulations.
• Used in the synthesis and research of bleomycin derivatives and conjugates for targeted therapy.

Basic Information

Product Name	Bleomycin A2
CAS No.	11116-31-7
Molecular Formula	C55H84N17O21S3
Molecular Weight	1415.6 g/mol
Synonyms	Bleomycin A2; Bleomycin A2 Hydrochloride; NSC-125066; Blenoxane (component); Bleomycin A2 (sulfate); Bleomycin A2 (copper-free); Bleomycin A2 (hydrochloride salt); Antibiotic BLM A2
EINECS	Contact for details

Quality Control

Our Bleomycin A2 is manufactured under strict quality systems to meet the rigorous standards required for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Bleomycin B2 Content (HPLC)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 5.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.