Description

11Beta,17Alpha,21-Trihydroxy-16Alpha-Methyl-1,4-Pregnadiene-3,20-Dione is a high-purity synthetic corticosteroid intermediate with significant pharmaceutical relevance. This compound serves as a critical building block in the synthesis of potent anti-inflammatory and immunosuppressive steroid APIs. It is essential for manufacturers in the pharmaceutical industry requiring reliable, high-quality raw materials for advanced drug development and production. Consistent quality and supply chain integrity are paramount for this key intermediate.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced corticosteroid active pharmaceutical ingredients (APIs).
• Anti-inflammatory Drug Synthesis: Used in the manufacturing of potent glucocorticoids for treating conditions like arthritis, asthma, and dermatitis.
• Immunosuppressant Production: Serves as a starting material for drugs that modulate the immune system.
• Research & Development: Utilized in pharmaceutical R&D for exploring new steroid-based therapeutics and metabolic pathways.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in laboratories.

Basic Information

Product Name	11Beta,17Alpha,21-Trihydroxy-16Alpha-Methyl-1,4-Pregnadiene-3,20-Dione
CAS No.	10417-63-7
Molecular Formula	C22H30O5
Molecular Weight	374.47 g/mol
Synonyms	16α-Methylprednisolone; 16α-Methyl-δ1-cortisol; 16α-Methylprednisolone (Intermediate); 11β,17α,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 16α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; 16-Methylprednisolone; 16α-Methyl-δ1-hydrocortisone
EINECS	233-889-0

Quality Control

Our 11Beta,17Alpha,21-Trihydroxy-16Alpha-Methyl-1,4-Pregnadiene-3,20-Dione is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.