Description

(11β,16α)-21-(Acetyloxy)-9-Chloro-11-Hydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-Pregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative, recognized for its specific structural modifications that confer unique biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical industry focusing on anti-inflammatory, immunosuppressive, and oncological applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid analogs and other specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new drug candidates with targeted efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	(11β,16α)-21-(Acetyloxy)-9-Chloro-11-Hydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-Pregna-1,4-Diene-3,20-Dione
CAS No.	10392-75-3
Molecular Formula	C₂₆H₃₃ClO₇
Molecular Weight	493.00 g/mol
Synonyms	9-Chloro-11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione 21-acetate; 9-Chloro-11β-hydroxy-16α,17α-isopropylidenedioxy-3,20-dioxopregna-1,4-dien-21-yl acetate; 9α-Chloro-11β-hydroxy-16α,17α-(isopropylidenedioxy)-1,4-pregnadiene-3,20-dione 21-acetate; Halcimonide EP Impurity C; Halcimonide Related Compound C; (11β,16α)-9-Chloro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our (11β,16α)-21-(Acetyloxy)-9-Chloro-11-Hydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-Pregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.