Description

9-Chloro Triamcinolone Acetonide is a halogenated derivative of the potent corticosteroid triamcinolone acetonide, serving as a key pharmaceutical intermediate. This compound is valued for its role in the synthesis of advanced topical and injectable corticosteroid formulations, where structural modification can influence potency, bioavailability, and metabolic stability. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers engaged in the development of anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel corticosteroid APIs and prodrugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new anti-inflammatory agents.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Process Chemistry: Employed in scale-up and optimization of manufacturing routes for halogenated steroid compounds.

Basic Information

Product Name	9-Chloro Triamcinolone Acetonide
CAS No.	10392-74-2
Molecular Formula	C24H30ClFO6
Molecular Weight	492.95 g/mol
Synonyms	9α-Chloro-11β,21-dihydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; 9α-Chlorotriamcinolone 16,17-acetonide; 9-Chloro-δ1-cortisol 16,17-acetonide; 9-Chlorofluoxyprednisolone acetonide; 9α-Chloro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 9-Chlorotriamcinolone acetonide
EINECS	Contact for details

Quality Control

Our 9-Chloro Triamcinolone Acetonide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.