Description

(3β,5β)-Tetrahydro 11-Deoxycorticosterone 21-Acetate CAS NO 10147-45-2 is a synthetic steroid derivative, specifically a tetrahydro form of a corticosterone precursor. This compound is of significant value as a key pharmaceutical intermediate in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers and research organizations engaged in the development and production of corticosteroid drugs and related therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of corticosteroid APIs and other steroid hormones.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism, receptor interactions, and enzyme inhibition.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in the development and scale-up of novel synthetic routes for steroid-based therapeutics.

Basic Information

Product Name	(3β,5β)-Tetrahydro 11-Deoxycorticosterone 21-Acetate
CAS No.	10147-45-2
Molecular Formula	C23H36O4
Molecular Weight	376.53 g/mol
Synonyms	11-Deoxycorticosterone 21-acetate, tetrahydro-; Tetrahydrodeoxycorticosterone acetate; 21-Acetoxy-3β,5β-pregnane-11,20-dione; 3β,5β-Tetrahydro-11-deoxycorticosterone acetate; 11-Deoxycorticosterone tetrahydro acetate; 3β,5β-THDOCA; Pregnane-11,20-dione, 21-(acetyloxy)-3,5-etrahydro-, (3β,5β)-
EINECS	Contact for details

Quality Control

Our (3β,5β)-Tetrahydro 11-Deoxycorticosterone 21-Acetate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.