Description

1,2,4,5-Tetrafluoro-3-Methoxy-6-Nitrobenzene is a high-value fluorinated aromatic building block characterized by its unique substitution pattern. This compound is critical for introducing specific fluorine and nitro functionalities into complex molecular architectures, enabling precise tuning of electronic and physical properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the synthesis of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides with enhanced activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the synthesis of electron-deficient aromatic cores for organic semiconductors and OLED materials.
• Dye and Pigment Research: Acts as a building block for creating novel fluorinated dyes with unique colorfastness and stability properties.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	1,2,4,5-Tetrafluoro-3-Methoxy-6-Nitrobenzene
CAS No.	1887-73-6
Molecular Formula	C7H3F4NO3
Molecular Weight	225.10 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-methoxynitrobenzene; 4-Methoxy-2,3,5,6-tetrafluoronitrobenzene; 1-Methoxy-2,3,5,6-tetrafluoro-4-nitrobenzene; 3-Methoxy-2,4,5,6-tetrafluoronitrobenzene; Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro-; Tetrafluoromethoxynitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 1,2,4,5-Tetrafluoro-3-Methoxy-6-Nitrobenzene is produced and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.