Description

[(5S,8S,9S,10S,13S,14S,17S)-10,13-Dimethyl-3-Oxo-2-(2,2,2-Trifluoroacetyl)-1,2,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydrocyclopenta[a]phenanthren-17-yl] Acetate is a high-purity, fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate or reference standard for the creation of novel therapeutic agents, particularly those targeting hormonal pathways or requiring enhanced metabolic stability. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluorinated steroid-based drugs, leveraging the trifluoroacetyl group for improved pharmacokinetic properties.
• Reference Standard: Used in analytical method development and validation for quality control (QC) and quality assurance (QA) in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating steroid receptor interactions, enzyme inhibition, and metabolic pathways.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) synthesis.
• Academic Research: Utilized in universities and research institutes for exploring new synthetic methodologies and structure-activity relationships (SAR) of steroid analogs.
• Custom Synthesis: A precursor for the contract manufacturing of specialized, high-value target molecules for clinical trials.

Basic Information

Item	Details
Product Name	[(5S,8S,9S,10S,13S,14S,17S)-10,13-Dimethyl-3-Oxo-2-(2,2,2-Trifluoroacetyl)-1,2,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydrocyclopenta[a]phenanthren-17-yl] Acetate
CAS No.	1880-36-0
Molecular Formula	C23H29F3O4
Molecular Weight	426.48 g/mol
Synonyms	17β-Acetoxy-2,2,2-trifluoro-3-oxoandrost-4-en-17-yl acetate (common name); 2,2,2-Trifluoro-3-oxoandrost-4-en-17β-yl acetate; 3-Oxo-2-(2,2,2-trifluoroacetyl)-androst-4-en-17β-yl acetate; Fluorinated Androstene Derivative; TFAA Steroid Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.