Description

Doxibetasol is a synthetic corticosteroid compound with significant pharmacological activity. This high-purity active pharmaceutical ingredient (API) is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical component in advanced therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions developing topical and systemic treatments for dermatological and inflammatory conditions.

Application

• Pharmaceutical API: Serves as the active ingredient in the formulation of corticosteroid-based medications.
• Topical Dermatological Preparations: Used in creams, ointments, and lotions for treating conditions like eczema, psoriasis, and contact dermatitis.
• Systemic Anti-inflammatory Drugs: A key intermediate in the synthesis of oral or injectable formulations for managing severe inflammation.
• Veterinary Medicine: Employed in anti-inflammatory and anti-pruritic treatments for animals.
• Biomedical Research: Used as a reference standard and in preclinical studies to investigate glucocorticoid receptor activity and metabolic pathways.
• Compounding Pharmacy: A raw material for custom-formulated medications to meet specific patient needs.

Basic Information

Product Name	Doxibetasol
CAS No.	1879-77-2
Molecular Formula	C24H31FO5
Molecular Weight	418.50 g/mol
Synonyms	9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16β-methylprednisolone; Doxybetasol; Desoximetasone Impurity C; Desoxymetasone; SQ-15101; Fluormethylprednisolon; NSC-121154
EINECS	217-522-8

Quality Control

Our Doxibetasol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and detailed Certificates of Analysis (COA) upon request, confirming compliance with relevant specifications for identity, purity, and impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.