Description

Dexamethasone 21-(3-Phenylpropionate) is a potent, long-acting ester prodrug of the glucocorticoid dexamethasone. This specific chemical derivative is engineered to enhance lipophilicity and prolong the duration of action, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry for the development of injectable corticosteroid formulations and other high-potency therapeutic agents.

Application

• Key intermediate in the synthesis of long-acting injectable corticosteroid pharmaceuticals.
• Research and development of novel prodrug formulations for enhanced drug delivery and bioavailability.
• Manufacturing of specialized anti-inflammatory and immunosuppressive medications.
• Production of reference standards for analytical and quality control laboratories.
• Used in preclinical and clinical studies investigating sustained-release drug delivery systems.

Basic Information

Product Name	Dexamethasone 21-(3-Phenylpropionate)
CAS No.	1879-72-7
Molecular Formula	C30H37FO6
Molecular Weight	512.61 g/mol
Synonyms	Dexamethasone 21-Phenylpropionate; Dexamethasone 21-(3-Phenylpropanoate); 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(3-phenylpropionate); Dexamethasone Phenylpropionate; NSC 113927
EINECS	Contact for details

Quality Control

Our Dexamethasone 21-(3-Phenylpropionate) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.