Description

Prednisolone Sodium Succinate CAS NO 1715-33-9 is a water-soluble ester salt of the potent glucocorticoid prednisolone, designed for rapid systemic delivery. This compound is critical for its potent anti-inflammatory and immunosuppressive effects, offering a fast-acting therapeutic solution. It is primarily required by the pharmaceutical industry for the formulation of injectable and ophthalmic medications, serving as a key active pharmaceutical ingredient (API) for treating severe allergic reactions, inflammatory conditions, and certain autoimmune disorders.

Application

• Injectable Corticosteroid Formulations: As a key API in emergency injectables for rapid anti-inflammatory and immunosuppressive action.
• Ophthalmic Solutions and Suspensions: Used in eye drops and ointments to treat inflammatory eye conditions such as uveitis and allergic conjunctivitis.
• Hospital and Clinical Infusions: For the preparation of intravenous (IV) or intramuscular (IM) solutions to manage acute disease flare-ups.
• Veterinary Pharmaceutical Products: Employed in anti-inflammatory treatments for companion and livestock animals.
• Research and Development: Serves as a reference standard and biochemical tool in pharmacological and metabolic studies.
• Parenteral Nutrition Adjuncts: In specific therapeutic regimens where systemic corticosteroid support is required.

Basic Information

Product Name	Prednisolone Sodium Succinate
CAS No.	1715-33-9
Molecular Formula	C25H31NaO8
Molecular Weight	482.50 g/mol
Synonyms	Prednisolone 21-Hemisuccinate Sodium Salt; Sodium Prednisolone Succinate; Prednisolone Succinate Sodium; Soluble Prednisolone; NSC-39415; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(Sodium Succinate); PSS; Prednisolone 21-Sodium Succinate
EINECS	217-008-3

Quality Control

Our Prednisolone Sodium Succinate is manufactured and tested under strict quality management systems. We ensure compliance with relevant pharmacopeial standards such as USP and EP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, guaranteeing it meets the stringent requirements for pharmaceutical ingredient use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
pH (5% solution)	7.0 - 8.5
Specific Rotation	+115° to +125° (c=1 in H2O)
Bacterial Endotoxins	< 0.17 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.