Description

3Beta,11Alpha,17-Trihydroxy-16Alpha-Methyl-5Alpha-Pregnan-20-One is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical manufacturing. This compound matters for its critical role in the synthesis of complex therapeutic agents, particularly within the steroid hormone class. Pharmaceutical R&D and production facilities require this material for developing and scaling up active pharmaceutical ingredients (APIs) with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic compounds targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules in pilot plants and manufacturing.
• Biochemical Research: Utilized in studies investigating steroid metabolism, enzyme interactions, and biological pathways.

Basic Information

Product Name	3Beta,11Alpha,17-Trihydroxy-16Alpha-Methyl-5Alpha-Pregnan-20-One
CAS No.	1635-20-7
Molecular Formula	C22H36O4
Molecular Weight	364.52 g/mol
Synonyms	16α-Methyl-11α,17β-dihydroxy-3β-hydroxy-5α-pregnan-20-one; 16α-Methyl-11α,17β,21-trihydroxy-5α-pregnan-3,20-dione derivative; 3β,11α,17-Trihydroxy-16α-methyl-5α-pregnan-20-one; 16α-Methyl-11α,17β-dihydroxypregnenolone analog; (3β,5α,11α,16α)-16-Methyl-3,11,17-trihydroxypregnan-20-one; 16-Methyl-11α,17β,21-trihydroxypregnenolone intermediate; 1635-20-7; NSC 113986
EINECS	Contact for details

Quality Control

Our 3Beta,11Alpha,17-Trihydroxy-16Alpha-Methyl-5Alpha-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.