Description

6α-Methyl Hydrocortisone CAS NO 1625-39-4 is a synthetic corticosteroid derivative, structurally related to hydrocortisone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex corticosteroid drugs and anti-inflammatory medications.
• Biochemical Research: Used as a reference standard or active agent in studies investigating glucocorticoid receptor activity and metabolic pathways.
• Steroid Chemistry Development: Serves as a precursor for the development of new steroid analogs with modified potency and selectivity profiles.
• Veterinary Medicine: Potential use in formulating anti-inflammatory treatments for animal health applications.
• Cosmeceutical R&D: Investigated for potential applications in high-end dermatological formulations targeting inflammation.

Basic Information

Product Name	6α-Methyl Hydrocortisone
CAS No.	1625-39-4
Molecular Formula	C22H32O5
Molecular Weight	376.49 g/mol
Synonyms	6α-Methylhydrocortisone; 6α-Methylcortisol; 11β,17α,21-Trihydroxy-6α-methylpregn-4-ene-3,20-dione; 6α-Methyl-11β,17α,21-trihydroxypregn-4-ene-3,20-dione; NSC 47439; Medrol Intermediate; 6-Methylhydrocortisone
EINECS	Contact for details

Quality Control

Our 6α-Methyl Hydrocortisone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider maintaining the material under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.