Description

9-Fluoro-16A,17-(Isopropylidenedioxy)Corticosterone is a synthetic fluorinated corticosteroid derivative, a key intermediate in advanced pharmaceutical research and development. Its value lies in its role as a critical building block for creating novel anti-inflammatory and immunosuppressive agents with enhanced potency and metabolic stability. This high-purity intermediate is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on developing next-generation steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the production of novel fluorinated corticosteroids.
• Anti-inflammatory Drug Research: Serves as a core scaffold for developing new compounds targeting inflammatory pathways with improved efficacy.
• Immunosuppressant Development: Used in research programs aimed at creating new immunosuppressive agents for autoimmune diseases and organ transplantation.
• Metabolic Stability Studies: The fluorinated structure is utilized to study and enhance the metabolic profile and half-life of steroid molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Contract Research: Fundamental material for mechanistic studies and structure-activity relationship (SAR) exploration in steroid chemistry.

Basic Information

Product Name	9-Fluoro-16A,17-(Isopropylidenedioxy)Corticosterone
CAS No.	1524-86-3
Molecular Formula	C24H33FO5
Molecular Weight	420.52 g/mol
Synonyms	9-Fluoro-16α,17-Isopropylidenedioxycorticosterone; 9-Fluoro-16α,17-[(1-Methylethylidene)bis(oxy)]-pregn-4-ene-3,11,20-trione; 9-Fluoro-16α,17-Acetonidecorticosterone; 9-Fluoro-16α,17-O-Isopropylidene Corticosterone; 9-Fluoro-16α,17-(Acetonylidene)Corticosterone; 9-F-16,17-Acetonide Corticosterone; Fluorocortisone-16,17-acetonide intermediate
EINECS	Contact for details

Quality Control

Our 9-Fluoro-16A,17-(Isopropylidenedioxy)Corticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.