Description

11-Beta,17-Alpha,21-Trihydroxy-5-β-Pregnane-3,20-Dione is a high-purity steroid derivative and a key intermediate in the synthesis of various pharmaceutical compounds. Its precise stereochemistry makes it a critical building block for producing corticosteroids and other bioactive molecules with specific therapeutic profiles. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis operations requiring a reliable source of high-quality steroid intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in medicinal chemistry for the discovery and development of new steroidal drugs and hormone analogs.
• Biochemical Research: Serves as a standard or reference compound in studies investigating steroid metabolism and receptor interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized steroid-based compounds.

Basic Information

Item	Details
Product Name	11-Beta,17-Alpha,21-Trihydroxy-5-β-Pregnane-3,20-Dione
CAS No.	1482-50-4
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	5β-Pregnan-3,20-dione, 11β,17α,21-trihydroxy-; 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione; 11β,17α,21-Trihydroxy-5β-pregnan-3,20-dione; 5β-Pregnane-3,20-dione, 11β,17α,21-trihydroxy-; Tetrahydrocortisone; 5β-Tetrahydrocortisone; 3α,5β-Tetrahydrocortisone; Urocortisone
EINECS	Contact for details

Quality Control

Our 11-Beta,17-Alpha,21-Trihydroxy-5-β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.