Description

(7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,8α,11-Pentahydroxy-7β,10α-Bis[[2,3,6-Trideoxy-3-(Dimethylamino)-α-L-Lyxo-Hexopyranosyl]Oxy]-5,12-Naphthacenedione is a complex, high-purity anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical intermediate or reference standard for the synthesis and analytical characterization of novel therapeutic agents, particularly in oncology. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation cancer treatments, antibiotics, and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathways for novel anthracycline-based chemotherapeutic agents.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (HPLC, LC-MS) of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating the mechanism of action, structure-activity relationships (SAR), and DNA-intercalation properties of anthracycline compounds.
• Antibiotic Research: Acts as a precursor or model compound in the development of new classes of antibiotics derived from natural product scaffolds.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for discovery chemistry and preclinical studies.

Basic Information

Product Name	(7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,8α,11-Pentahydroxy-7β,10α-Bis[[2,3,6-Trideoxy-3-(Dimethylamino)-α-L-Lyxo-Hexopyranosyl]Oxy]-5,12-Naphthacenedione
CAS No.	1403-81-2
Molecular Formula	C₄₁H₅₃NO₁₈
Molecular Weight	855.86 g/mol
Synonyms	7-Deoxy-13-dihydrodaunorubicin; 7-Deoxy-13-dihydrodaunomycin; 7-Deoxy-13-dihydrodaunorubicinol; Daunorubicin, 7-deoxy-13-dihydro-; 13-Dihydro-7-deoxydaunorubicin; Antibiotic MA 144 M1; (7R)-8-Ethyl-7,8,9,10-tetrahydro-1,4,6,8,11-pentahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our (7R)-8-Ethyl-7,8,9,10-Tetrahydro-1,4,6,8α,11-Pentahydroxy-7β,10α-Bis[[2,3,6-Trideoxy-3-(Dimethylamino)-α-L-Lyxo-Hexopyranosyl]Oxy]-5,12-Naphthacenedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C). Keep the container tightly sealed in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.