Description

9-Fluoro-11Beta,21-Dihydroxypregna-1,4,16-Triene-3,20-Dione 21-Acetate is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its specific fluorinated and triene-modified structure, which is essential for creating novel therapeutic agents with targeted biological activity. This compound is primarily needed by pharmaceutical manufacturers and R&D laboratories focused on developing next-generation corticosteroids, anti-inflammatory drugs, and other specialized steroid-based therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated corticosteroid drugs and anti-inflammatory agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new steroid-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules in pilot plants.
• Biochemical Research: Investigated for its interaction with steroid hormone receptors to understand metabolic pathways and mechanisms.

Basic Information

Product Name	9-Fluoro-11Beta,21-Dihydroxypregna-1,4,16-Triene-3,20-Dione 21-Acetate
CAS No.	1250-85-7
Molecular Formula	C23H27FO6
Molecular Weight	418.46 g/mol
Synonyms	9-Fluoro-11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate; 9-Fluoro-11β,21-dihydroxy-1,4,16-pregnatriene-3,20-dione 21-acetate; 21-Acetoxy-9-fluoro-11β-hydroxy-1,4,16-pregnatriene-3,20-dione; 9-Fluoro-11β-hydroxy-16-methyleneprednisolone 21-acetate; Fluocortolone 21-acetate derivative; 1,4,16-Pregnatriene-3,20-dione, 9-fluoro-11β,21-dihydroxy-, 21-acetate; 9-Fluoro-11β-hydroxy-16-methyleneprednisolone acetate
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,21-Dihydroxypregna-1,4,16-Triene-3,20-Dione 21-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, and is supported by a detailed Certificate of Analysis (COA). We adhere to relevant industry standards and can provide material tailored to specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.