Description

Methdilazine Hydrochloride (200 Mg) is a high-purity pharmaceutical-grade active pharmaceutical ingredient (API) supplied as a white to off-white crystalline powder. This compound is a phenothiazine derivative with significant antihistaminic and antipruritic properties, making it a critical component for therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of prescription medications targeting allergic conditions and severe itching. Our supply ensures consistent quality and reliable availability for global B2B partners.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription antihistamine and antipruritic (anti-itch) medications.
• Dermatological Preparations: Formulated into topical creams, ointments, or lotions for treating skin allergies, urticaria (hives), and eczema.
• Oral Solid Dosage Forms: Manufactured into tablets or capsules for systemic treatment of allergic reactions and pruritus.
• Veterinary Pharmaceuticals: Used in veterinary medicine for managing allergic dermatitis and pruritus in animals.
• Clinical Research: Serves as a reference standard or raw material in pharmacological studies and clinical trials.
• Generic Drug Manufacturing: Key raw material for producing generic versions of branded antihistamine drugs.

Basic Information

Product Name	Methdilazine Hydrochloride (200 Mg)
CAS No.	1229-35-2
Molecular Formula	C₁₈H₂₀N₂S • HCl
Molecular Weight	332.89 g/mol
Synonyms	Methdilazine HCl; 10-[(1-Methyl-3-pyrrolidinyl)methyl]phenothiazine Hydrochloride; Tacaryl Hydrochloride; Dilosyn Hydrochloride; Metapyrin; Methdilazinum Hydrochloricum; UNII-0Q1LX2C97J; 1-Methyl-4-[10H-phenothiazin-10-ylmethyl]piperidine Hydrochloride
EINECS	214-974-0

Quality Control

Our Methdilazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial standards for identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for pharmaceutical use. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.