Antiemetics and Emetics

Antiemetics and Emetics

Antiemetics and emetics are pharmacological agents with opposite functions-suppressing or inducing vomiting. Antiemetics include serotonin 5-HT3 antagonists, dopamine antagonists, antihistamines, NK1 receptor antagonists, and anticholinergics, all of which reduce nausea by blocking emetogenic pathways in the central nervous system or gastrointestinal tract. They are used in chemotherapy-induced nausea, postoperative care, motion sickness, pregnancy-related nausea, and gastrointestinal disorders. Emetics, such as apomorphine, stimulate the vomiting center to remove ingested toxins. Because inducing vomiting carries medical risks, emetics are used sparingly and only under supervision. Antiemetics greatly improve comfort, treatment adherence, and quality of life in patients susceptible to severe nausea.

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