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(2S,3R,4E)-2-(Tetracosanoylamino)-1-[4-O-[4-O-[3-O-(2-acetylamino-2-deoxy-β-D-galactopyranosyl)-α-D-galactopyranosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyloxy]-4-octadecen-3-ol CAS NO 82006-00-6


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CAS No.:82006-00-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S,3R,4E)-2-(Tetracosanoylamino)-1-[4-O-[4-O-[3-O-(2-acetylamino-2-deoxy-β-D-galactopyranosyl)-α-D-galactopyranosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyloxy]-4-octadecen-3-ol is a complex, high-purity glycosphingolipid derivative, a critical building block in advanced biochemical research and development. This compound is essential for studying cell membrane structure, signal transduction, and carbohydrate-protein interactions. It is primarily utilized by research institutions and pharmaceutical companies focused on glycobiology, immunology, and the development of novel therapeutics.

Application

  • Biochemical Research Standard: Used as a reference standard in mass spectrometry and chromatography for the identification and quantification of complex lipids.
  • Glycobiology Studies: Critical for investigating the role of specific glycosphingolipids in cell recognition, adhesion, and signaling pathways.
  • Immunology Research: Applied in studies of antigen presentation and the modulation of immune responses, particularly related to lipid rafts.
  • Pharmaceutical Development: Serves as a key intermediate or reference molecule in the R&D of targeted therapies, vaccines, and diagnostic agents.
  • Enzyme Substrate/Inhibitor: Used to study the activity and specificity of glycosidases and glycosyltransferases.
  • Membrane Biophysics: Employed in model membrane systems (e.g., liposomes) to study lipid-lipid and lipid-protein interactions.

Basic Information

Item Details
Product Name (2S,3R,4E)-2-(Tetracosanoylamino)-1-[4-O-[4-O-[3-O-(2-acetylamino-2-deoxy-β-D-galactopyranosyl)-α-D-galactopyranosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyloxy]-4-octadecen-3-ol
CAS No. 82006-00-6
Molecular Formula C86H156N2O22
Molecular Weight 1569.18 g/mol
Synonyms Ganglioside GM1b (IV3Neu5AcGgOse4Cer); Asialo-GM1; GA1; β-Gal-(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1↔1)-Ceramide (deprotected form); GgOse4Cer; Globoside; Glycosphingolipid GA1; 2-Acetamido-2-deoxy-3-O-β-D-galactopyranosyl-D-galactose derivative
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Quality Control

Our high-purity biochemicals are produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, purity, and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 3.0 %
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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