Description

Piperazine-N,N'-Bis(2-Hydroxypropanesulfonic Acid) Sesquisodium Salt is a high-purity, water-soluble zwitterionic buffer agent widely recognized for its excellent buffering capacity in the physiological pH range. This compound matters for its ability to maintain precise pH stability in complex biochemical and diagnostic systems, ensuring reliable and reproducible results. It is primarily needed by manufacturers in the biotechnology, pharmaceutical, and in-vitro diagnostic (IVD) industries for applications requiring stringent pH control.

Application

• IVD Reagent Formulation: A key buffering component in clinical diagnostic kits, including immunoassays and enzymatic tests, for stable pH maintenance.
• Biopharmaceutical Processing: Used in cell culture media and protein purification buffers to support cell growth and maintain protein stability.
• Molecular Biology: Serves as a buffer in PCR master mixes, electrophoresis running buffers, and nucleic acid hybridization solutions.
• Biochemical Research: Employed in enzyme kinetics studies, chromatography elution buffers, and other laboratory procedures requiring precise pH control.
• Cosmetic & Personal Care: Acts as a pH stabilizer and conditioning agent in high-performance skincare and haircare formulations.

Basic Information

Product Name	Piperazine-N,N'-Bis(2-Hydroxypropanesulfonic Acid) Sesquisodium Salt
CAS No.	108321-08-0
Molecular Formula	C10H18N2Na1.5O10S2
Molecular Weight	428.36 g/mol (anhydrous basis)
Synonyms	PIPES Sesquisodium Salt; 1,4-Piperazinediethanesulfonic Acid Sesquisodium Salt; PIPES Na Salt; 2,2'-(Piperazine-1,4-diyl)bis(ethanesulfonic acid) Sesquisodium Salt; Good's Buffer PIPES Sesquisodium Salt; PIPES Buffer Salt; PIPES-Na1.5; CAS 108321-08-0
EINECS	Contact for details

Quality Control

Our Piperazine-N,N'-Bis(2-Hydroxypropanesulfonic Acid) Sesquisodium Salt is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for sensitive applications in diagnostics and bioprocessing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Endotoxin (LAL)	< 0.25 EU/mg (for applicable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.