Description

Dextran Sulfate Sodium Salt is a high-purity, sulfated polysaccharide derivative widely used as a critical reagent in life science research and pharmaceutical development. Its primary value lies in its ability to induce experimental colitis in animal models, making it indispensable for studying inflammatory bowel disease (IBD) and evaluating potential therapeutics. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require a reliable and consistent compound for immunological studies, cell culture applications, and as a heparin substitute in various biochemical assays. We supply Dextran Sulfate Sodium Salt CAS NO 9011-18-1 in grades suitable for research and commercial applications.

Application

• Induction of Experimental Colitis: A key reagent for creating murine models of ulcerative colitis and inflammatory bowel disease (IBD) for preclinical research.
• Cell Culture & Virology: Used to enhance the infectivity of viruses like HIV in cell cultures and as a co-receptor binding inhibitor.
• Biochemical Research: Acts as a competitive inhibitor for heparin-binding proteins and is used in lipoprotein precipitation studies.
• Diagnostic Reagents: Employed as a component in certain diagnostic kits and buffers for clinical testing.
• Pharmaceutical Excipient: Investigated for use in controlled drug delivery systems due to its polyanionic character.
• Blood Coagulation Studies: Serves as a heparin analog in research related to blood clotting mechanisms.

Basic Information

Product Name	Dextran Sulfate Sodium Salt
CAS No.	9011-18-1
Molecular Formula	(C6H7Na3O14S3)n
Molecular Weight	Variable (typically 5,000 - 500,000 Da grades available)
Synonyms	Dextran Sulfate Sodium; Sodium Dextran Sulfate; DSS; Dextran Sodium Sulfate; Dextran Sulphate Sodium Salt; Dextran Hydrogen Sulfate Sodium Salt; Poly[(3,4-dihydroxy-1,5-hexadiene-1,1-diyl)sulfonic acid] sodium salt
EINECS	Contact for details

Quality Control

Our Dextran Sulfate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for molecular weight distribution, sulfur content, purity, and biological activity. Certificates of Analysis (COA) detailing parameters such as assay, pH, heavy metals, and endotoxin levels (where applicable) are provided to guarantee consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (Sulfur Content)	16.0 - 20.0 %
pH (1% solution)	5.0 - 7.5
Heavy Metals	< 20 ppm
Molecular Weight (Average)	5,000 / 40,000 / 500,000 Da (or as requested)
Loss on Drying	< 10.0 %
Residue on Ignition (Sulfated Ash)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.