Description

Mmae-Smcc CAS NO 2021179-11-1 is a heterobifunctional crosslinking agent designed for advanced bioconjugation applications. This compound is critical for creating stable, site-specific linkages between biomolecules, enabling the development of next-generation therapeutics and diagnostics. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for antibody-drug conjugate (ADC) development, protein labeling, and the creation of novel diagnostic assays.

Application

• Key reagent in the synthesis of Antibody-Drug Conjugates (ADCs) for targeted cancer therapy.
• Site-specific protein-protein crosslinking for structural studies and engineered protein complexes.
• Conjugation of peptides, oligonucleotides, or small molecule drugs to carrier proteins or antibodies.
• Surface functionalization and immobilization of biomolecules for biosensor and diagnostic device development.
• Preparation of stable immunogen conjugates for vaccine research.
• Tool compound in chemical biology for studying protein interactions and cellular pathways.

Basic Information

Product Name	Mmae-Smcc
CAS No.	2021179-11-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Maleimidocaproyl-monomethyl auristatin E succinimidyl carbamate; MMAE-SMCC Conjugate; MC-MMAE; Auristatin E SMCC derivative; SMCC-linked MMAE; ADC linker-payload MMAE-SMCC; N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate-MMAE
EINECS	Contact for details

Quality Control

Our Mmae-Smcc is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.