Description

1,4-Piperazinedipropanesulfonic Acid is a high-purity biochemical buffer and organic intermediate of significant commercial and research importance. Its value lies in its excellent buffering capacity in the physiological pH range, making it a critical component for maintaining stable conditions in sensitive processes. This compound is essential for manufacturers and researchers in the pharmaceutical, biotechnology, and diagnostic reagent industries, where precise pH control is paramount for product efficacy and experimental reproducibility.

Application

• Biochemical Buffer: Used in cell culture media, enzyme assays, and protein purification protocols to maintain precise physiological pH conditions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific biological pathways.
• Diagnostic Reagent Formulation: A component in the formulation of buffers for diagnostic kits and assays, ensuring accuracy and stability of test results.
• Molecular Biology Research: Employed in PCR, electrophoresis, and other molecular biology techniques that require highly stable buffering environments.
• Cosmetic & Personal Care: Utilized as a pH adjuster and stabilizer in high-end cosmetic formulations where skin compatibility is crucial.
• Chemical Synthesis: Acts as a versatile intermediate for further chemical modifications, leveraging its piperazine and sulfonic acid functional groups.

Basic Information

Product Name	1,4-Piperazinedipropanesulfonic Acid
CAS No.	5625-56-9
Molecular Formula	C10H22N2O6S2
Molecular Weight	330.42 g/mol
Synonyms	PIPES Dipropanesulfonic Acid; 1,4-Piperazinebis(propanesulfonic acid); Piperazine-N,N'-bis(2-propanesulfonic acid); PIPES Dipropionic Acid Sulfonate; 3,3'-(Piperazine-1,4-diyl)dipropane-1-sulfonic Acid; Buffer PIPES; Good's Buffer PIPES
EINECS	227-070-0

Quality Control

Our 1,4-Piperazinedipropanesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
pH (1% Solution)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.