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[6-[6-[(3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-2,4-dihydro-1H-tetr acen-1-yl)oxy]-4-dimethylamino-2-methyl-oxan-3-yl]oxy-2-methyl-3-(6-me thyl-5-oxo-oxan-2-yl)oxy-oxan-4-yl] acetate CAS NO 81975-92-0
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CAS No.:81975-92-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
[6-[6-[(3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-4-dimethylamino-2-methyl-oxan-3-yl]oxy-2-methyl-3-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-4-yl] acetate is a complex, semi-synthetic tetracycline derivative with significant biological activity. This compound matters for its role as a key intermediate in the synthesis of advanced antibiotic and pharmaceutical agents, offering a pathway to novel therapeutics. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development of next-generation antimicrobials and specialized chemical synthesis.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel tetracycline-class antibiotics and other therapeutic agents.
- Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships and develop new antibacterial compounds.
- Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with specific chiral centers and functional groups.
- Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
- Bioconjugation Studies: Utilized in research exploring the attachment of bioactive molecules to carriers or probes due to its reactive sites.
Basic Information
| Product Name | [6-[6-[(3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-4-dimethylamino-2-methyl-oxan-3-yl]oxy-2-methyl-3-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-4-yl] acetate |
| CAS No. | 81975-92-0 |
| Molecular Formula | C41H47NO17 |
| Molecular Weight | 825.82 g/mol |
| Synonyms | Doxycycline 9-acetate; 9-Acetyldoxycycline; 6-Deoxy-5-oxytetracycline 9-acetate; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide 9-acetate; α-6-Deoxy-5-oxytetracycline 9-acetate; Doxycycline acetate (9-); (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 9-acetate |
| EINECS | Contact for details |
Quality Control
Our [6-[6-[(3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-4-dimethylamino-2-methyl-oxan-3-yl]oxy-2-methyl-3-(6-methyl-5-oxo-oxan-2-yl)oxy-oxan-4-yl] acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from exposure to light to maintain stability and potency.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to orange-yellow powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% Any single impurity ≤ 2.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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