Description

9-Minocycline is a semi-synthetic tetracycline derivative with potent antibacterial activity. This compound is valued for its broad-spectrum efficacy and serves as a key intermediate in the synthesis of advanced pharmaceutical agents. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on antibiotic development and production.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of minocycline hydrochloride and other related antibiotic APIs.
• Antibacterial Research: Critical reference standard and active component in microbiological and pharmacological studies.
• Veterinary Medicine: Used in the development of antibacterial treatments for animal health.
• Biochemical Reagent: Employed in laboratory settings for studying bacterial protein synthesis inhibition.
• Fine Chemical Synthesis: Building block for creating novel tetracycline-class derivatives with modified properties.

Basic Information

Product Name	9-Minocycline
CAS No.	10118-89-5
Molecular Formula	C₂₃H₂₇N₃O₇
Molecular Weight	457.48 g/mol
Synonyms	9-Minocycline; Minocycline Impurity F; 7-Dimethylamino-6-deoxy-6-demethyltetracycline; 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide
EINECS	Contact for details

Quality Control

Our 9-Minocycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.