Description

Clomocycline CAS NO 1181-54-0 is a semi-synthetic tetracycline antibiotic derived from chlortetracycline. This compound is valued for its broad-spectrum antibacterial activity, making it a critical intermediate in pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and life science research sectors for developing antibiotic formulations and conducting microbiological studies.

Application

• Pharmaceutical Active Ingredient: Serves as a key intermediate in the synthesis of finished antibiotic dosage forms.
• Veterinary Medicine: Used in the development of antibacterial treatments for livestock and companion animals.
• Microbiological Research: Employed as a standard or reagent in studies investigating bacterial resistance and antibiotic mechanisms of action.
• Reference Standard: Utilized in quality control laboratories as a high-purity standard for analytical method development and validation.
• Biochemical Studies: Applied in research exploring protein synthesis inhibition and other cellular processes affected by tetracyclines.

Basic Information

Item	Details
Product Name	Clomocycline
CAS No.	1181-54-0
Molecular Formula	C22H23ClN2O8
Molecular Weight	478.88 g/mol
Synonyms	7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; Clomocycline; NSC-64394; Antibiotic U 24973A; Methylchlor tetracycline; 7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide
EINECS	214-644-9

Quality Control

Our Clomocycline is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure it meets high-purity standards suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.