Description

Anhydrotetracycline Hydrochloride is a chemically modified derivative of tetracycline, valued for its role as a key intermediate and reference standard in antibiotic research and development. This compound is critical for studying bacterial resistance mechanisms and for the synthesis of novel semi-synthetic tetracycline-class antibiotics. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel tetracycline antibiotics and their derivatives.
• Biochemical Research: Used as a reference standard and tool compound in studies of protein synthesis inhibition and bacterial ribosome function.
• Microbiology Studies: Employed in research investigating tetracycline resistance mechanisms (e.g., efflux pumps, ribosomal protection).
• Analytical Standard: Serves as a high-purity calibrant for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Veterinary Pharmaceutical Development: Used in R&D for animal health products within the antibiotic class.

Basic Information

Product Name	Anhydrotetracycline Hydrochloride
CAS No.	13803-65-1
Molecular Formula	C₂₂H₂₂N₂O₇·HCl
Molecular Weight	460.88 g/mol
Synonyms	4-Epianhydrotetracycline Hydrochloride; ATC HCl; Anhydrotetracycline HCl; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-; 4-Epi-ATC Hydrochloride; NSC 643120; Tetracycline impurity
EINECS	Contact for details

Quality Control

Our Anhydrotetracycline Hydrochloride is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical tests including HPLC for assay and related substances, and spectroscopic methods for identification. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.