Description

Doxycycline Hydrochloride CAS NO 10592-13-9 is a broad-spectrum tetracycline antibiotic widely used in both human and veterinary medicine. Its primary value lies in its effectiveness against a wide range of bacterial infections, including those caused by intracellular pathogens. This compound is essential for pharmaceutical manufacturers, research institutions, and veterinary product formulators requiring a reliable and potent active pharmaceutical ingredient (API).

Application

• Pharmaceutical API: Core ingredient in oral capsules, tablets, and injectable formulations for treating respiratory, urinary, and skin infections.
• Veterinary Medicine: Used in medicated feeds, premixes, and injectables for livestock, poultry, and companion animals to control bacterial diseases.
• Research & Development: Serves as a critical reference standard and biochemical tool in microbiological and pharmacological studies.
• Malaria Prophylaxis: Employed in specific formulations for the prevention of malaria in travelers to endemic regions.
• Acne Treatment: A key component in systemic and topical treatments for severe acne vulgaris.
• Periodontal Disease: Used in specialized dental applications for the management of aggressive periodontitis.

Basic Information

Product Name	Doxycycline Hydrochloride
CAS No.	10592-13-9
Molecular Formula	C₂₂H₂₄N₂O₈·HCl
Molecular Weight	480.90 g/mol
Synonyms	Doxycycline HCl; Vibramycin; Doxycycline Monohydrochloride; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride; GS 3065; Doxycycline Hydrochloride Hemihydrate Hemiethanolate; Doxycycline Hydrochloride Hemihydrate; Doxycycline Hydrochloride Hydrate
EINECS	234-208-6

Quality Control

Our Doxycycline Hydrochloride is manufactured under strict quality management systems. It is typically tested to meet or exceed relevant pharmacopoeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles to ensure it meets the stringent requirements for pharmaceutical and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to yellow-orange crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	2.0 - 3.0
Water (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.