Description

7-Chloro-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,9,10,12,12A-Hexahydroxy-1,11-Dioxo-2-Naphthacenecarboxamide is a high-purity, complex tetracycline derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in providing a reliable and consistent building block for the research and development of novel antibiotic and therapeutic agents. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and fine chemical producers focused on anti-infective drug discovery and specialized chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel tetracycline-class antibiotics and other therapeutic molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new anti-infective agents.
• Biochemical Research: Employed as a tool compound in microbiological and pharmacological studies to investigate bacterial protein synthesis inhibition.
• Fine Chemical Synthesis: Serves as a specialized building block for the preparation of complex, high-value chemical entities in custom synthesis projects.

Basic Information

Product Name	7-Chloro-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,9,10,12,12A-Hexahydroxy-1,11-Dioxo-2-Naphthacenecarboxamide
CAS No.	13227-28-6
Molecular Formula	C₂₂H₂₅ClN₂O₉
Molecular Weight	496.90 g/mol
Synonyms	7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,9,10,12,12a-hexahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,9,10,12,12a-hexahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide (related); 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline derivative; Tetracycline derivative intermediate
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,9,10,12,12A-Hexahydroxy-1,11-Dioxo-2-Naphthacenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.