Description

Tetracycline Hydrochloride is a broad-spectrum antibiotic belonging to the tetracycline class. It is a critical active pharmaceutical ingredient (API) valued for its effectiveness against a wide range of gram-positive and gram-negative bacteria, mycoplasmas, and other microorganisms. This compound is essential for manufacturers in the pharmaceutical industry, particularly for formulating oral dosage forms, veterinary medicines, and certain topical applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in human and veterinary antibiotic capsules, tablets, and oral suspensions.
• Veterinary Medicine: Formulation of medicated feeds, injectables, and powders for the treatment of bacterial infections in livestock, poultry, and companion animals.
• Topical Preparations: Incorporated into ointments, creams, and powders for treating skin infections and acne.
• Research & Development: Used as a standard or reagent in microbiological research, antibiotic resistance studies, and biochemical assays.
• Aquaculture: Application in fish farming for disease control, subject to local regulatory approvals.
• Preservative Studies: Investigational use in cell culture media and laboratory applications requiring bacteriostatic agents.

Basic Information

Product Name	Tetracycline Hydrochloride
CAS No.	1170-81-6
Molecular Formula	C₂₂H₂₅ClN₂O₈
Molecular Weight	480.90 g/mol
Synonyms	Tetracycline HCl; Achromycin V; Abricycline; Ambramycin; Cyclomycin; Deschlorobiomycin; Panmycin Hydrochloride; Polycycline Hydrochloride; Tetracyn Hydrochloride; (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
EINECS	214-590-8

Quality Control

Our Tetracycline Hydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant pharmacopoeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles, confirming it meets the stringent requirements for pharmaceutical ingredient use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	1.8 - 2.8
Specific Rotation	-240° to -255°
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 50 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.