Description

Doxycycline is a broad-spectrum, semi-synthetic tetracycline antibiotic. It is highly valued for its efficacy against a wide range of gram-positive and gram-negative bacteria, as well as certain atypical pathogens. This makes it a critical active pharmaceutical ingredient (API) for manufacturers in the human and veterinary pharmaceutical industries. Doxycycline CAS NO 10597-92-9 is essential for formulating treatments for respiratory infections, acne, malaria prophylaxis, and other bacterial diseases.

Application

• Human Pharmaceutical Formulations: Used as the active ingredient in capsules, tablets, and injectables for treating bacterial pneumonia, Lyme disease, chlamydia, and acne vulgaris.
• Veterinary Medicine: Incorporated into medicated feeds, oral pastes, and injectables for livestock, poultry, and companion animals to treat respiratory and systemic infections.
• Malaria Prophylaxis and Treatment: Employed in combination therapies for the prevention and treatment of malaria in regions with chloroquine-resistant strains.
• Research & Development: Serves as a key biochemical tool in microbiological research for studying bacterial protein synthesis and antibiotic resistance mechanisms.
• Topical Preparations: Used in gels and creams for the treatment of periodontal disease and certain skin conditions.

Basic Information

Product Name	Doxycycline
CAS No.	10597-92-9
Molecular Formula	C22H24N2O8
Molecular Weight	444.43 g/mol
Synonyms	Doxycycline Hydate; Doxycycline Monohydrate; Vibramycin; GS-3065; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrate; Doxycycline HCl (for the hydrochloride salt); α-6-Deoxy-5-oxytetracycline
EINECS	234-208-6

Quality Control

Our Doxycycline is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and BP. Every batch undergoes rigorous analytical testing including HPLC for assay and related substances, microbial limits, and residual solvent analysis to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	1.5% - 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.