Description

7-Chloro-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-1,4-Dioxo-2-Naphthacenecarboxamide 4-Hydrazone is a complex, high-purity chemical intermediate with significant synthetic utility. This compound is valued for its role as a key precursor in the development of advanced pharmaceutical agents and research chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for synthesizing novel therapeutic candidates and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel tetracycline-class antibiotics and other bioactive molecules.
• Research & Development: Used in medicinal chemistry for lead optimization and the development of new chemical entities (NCEs) targeting bacterial infections.
• Biochemical Research: Serves as a tool compound in microbiological and enzymatic studies to investigate mechanisms of action.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	7-Chloro-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-1,4-Dioxo-2-Naphthacenecarboxamide 4-Hydrazone
CAS No.	1177-81-7
Molecular Formula	C₂₁H₂₂ClN₃O₈
Molecular Weight	479.87 g/mol
Synonyms	7-Chlorotetracycline hydrazone; 7-Chloro-4-hydrazinocarbonyl-4a,5,5a,6,11,12a-hexahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-CTC hydrazone; Tetracycline, 7-chloro-, hydrazone; 7-Chloro-4-demethylamino-4-hydrazinocarbonyltetracycline; 7-Chloro-4-(hydrazinecarbonyl)tetracycline; 7-Chloro-4-(hydrazinylcarbonyl)tetracycline; 7-Chloro-4-(aminocarbonylhydrazino)tetracycline
EINECS	Contact for details

Quality Control

Our 7-Chloro-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-1,4-Dioxo-2-Naphthacenecarboxamide 4-Hydrazone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.