Description

Octanoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide, monohydrochloride is a chemically modified derivative of a complex anthracycline-like structure, designed for enhanced stability and specific biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors focusing on oncology and antibiotic drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel anthracycline-based antibiotics and chemotherapeutic agents.
• Anticancer Research: Used in preclinical studies to develop new drug candidates targeting DNA intercalation and topoisomerase inhibition.
• Antibiotic Development: Serves as a precursor for modifying the sugar moiety and side chains to improve pharmacokinetics and reduce toxicity in antibiotic analogs.
• Biochemical Research: Employed as a reference standard or probe in studies investigating the mechanism of action of complex glycosylated natural products.
• Process Chemistry: Used in scale-up and optimization studies for the production of high-value active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Octanoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide, monohydrochloride
CAS No.	80041-11-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Daunorubicin 13-(N-octanoyl)hydrazone monohydrochloride; 13-(N-Octanoyl)daunorubicin hydrazone HCl; Octanoic acid hydrazide derivative of daunorubicin hydrochloride; 13-Octanoylhydrazone of daunorubicin HCl; AD 198 derivative; N-L-Octanoyl-daunorubicin-13-hydrazone hydrochloride; (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside 13-(N-octanoyl)hydrazone monohydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Each batch is characterized and controlled using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be stored in a dry environment. For long-term storage, consider desiccant use and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.