Description

[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(3-methylbut-2-enoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid is a sophisticated, high-purity nucleotide analog designed for advanced research and development. This compound is critical for applications requiring precise biochemical modulation, particularly in the study of enzymatic pathways and cellular signaling. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions focused on drug discovery and molecular biology.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active component in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery programs.
• Biochemical Research: Used as a substrate, inhibitor, or probe in enzymatic studies to investigate kinase and phosphotransferase activity and mechanism.
• Proteomics & Molecular Biology: Employed in the study of protein-nucleotide interactions, signal transduction pathways, and the development of diagnostic assays.
• Nucleotide Chemistry: Acts as a specialized building block for the synthesis of modified oligonucleotides and other complex nucleotide derivatives with tailored properties.
• Cell Signaling Studies: Utilized to modulate intracellular second messenger systems, aiding in the exploration of metabolic regulation and cellular response mechanisms.

Basic Information

Product Name	[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(3-methylbut-2-enoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid
CAS No.	793193-48-3
Molecular Formula	C24H39N8O16P3S
Molecular Weight	828.60 g/mol
Synonyms	Adenosine triphosphate derivative, thioester-modified ATP analog; Prenaltered ATP analog; Modified nucleoside triphosphate; ATP-γ-S derivative; 2',3'-O-Isopropylideneadenosine 5'-(γ-thio)triphosphate analog; Nucleotide-based enzyme substrate; CAS 793193-48-3
EINECS	Contact for details

Quality Control

Our production of this high-grade nucleotide analog adheres to stringent quality protocols. Every batch is characterized and tested using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.