Description

[[[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is a high-purity, biologically active nucleotide derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool in the study of cellular energy metabolism, signal transduction, and nucleic acid synthesis. It is primarily required by biopharmaceutical companies, academic research institutions, and diagnostic manufacturers for applications in enzymology, molecular biology, and the development of novel therapeutics.

Application

• Biochemical Research: Used as a high-energy phosphate donor or substrate in enzymatic assays and studies of kinase, ATPase, and polymerase activity.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of nucleotide-based drugs, including antivirals and anticancer agents.
• Diagnostic Reagent Manufacturing: Incorporated into kits for measuring cellular energy status (e.g., ATP/ADP/AMP levels) and for metabolic profiling.
• Enzymology Studies: Essential for investigating the kinetics and mechanisms of enzymes involved in purine and pyrimidine metabolism.
• Cell Signaling Research: Utilized in studies of purinergic signaling pathways, which are crucial in immunology, neurology, and cardiology.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	[[[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS No.	78101-73-2
Molecular Formula	C20H30N10O27P5
Molecular Weight	1000.18 g/mol
Synonyms	P1,P5-Di(adenosine-5') pentaphosphate; Ap5A; Diadenosine pentaphosphate; Adenosine-5'-pentaphospho-5'-adenosine; Diadenosine-5',5'''-P1,P5-pentaphosphate; Penta-phosphoric acid di(adenosine-5'-) ester; 5'-Adenylyl P1,P5-bis(5'-adenosyl) pentaphosphate; Di(adenosine-5')-pentaphosphate
EINECS	Contact for details

Quality Control

Our [[[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in water or buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.