Description

Disodium 2-[[(4R)-4-[(3R,5S,7R,10S,13R,17R)-3-hydroxy-10,13-dimethyl-7-sulfonatooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate is a high-purity, water-soluble sulfonate derivative of a steroidal structure. This compound is valued for its role as a critical intermediate or reference standard in advanced pharmaceutical research and synthesis. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drug candidates.
• Research Chemical: Used as a reference standard or biochemical tool in academic and industrial research on steroid metabolism and receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific sulfonated steroidal motifs into target molecules.
• Analytical Standard: Serves as a high-purity calibrant for analytical methods like HPLC and LC-MS in quality control and metabolic studies.
• Bioconjugation Studies: The sulfonate groups can be utilized for conjugation chemistry in developing targeted drug delivery systems.

Basic Information

Product Name	Disodium 2-[[(4R)-4-[(3R,5S,7R,10S,13R,17R)-3-hydroxy-10,13-dimethyl-7-sulfonatooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
CAS No.	66874-12-2
Molecular Formula	C28H44NNa2O10S2
Molecular Weight	663.76 g/mol
Synonyms	Disodium 2-[(4R)-4-[(3R,5S,7R,10S,13R,17R)-3-Hydroxy-10,13-dimethyl-7-sulfonatooxy-1,2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanamido]ethanesulfonate; 7-Dehydrocholesterol disulfonate disodium salt derivative; Cholestane-3,7-diol, disulfate, disodium salt (isomer); Steroid disulfonate intermediate; 66874-12-2; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.